Resistance against Ehrlich Ascites Tumor Induced by DEPC-treated Ehrlich Cells
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منابع مشابه
Antisera against the Ehrlich Ascites Tumor*
Newborn rabbits were made immunologically tolerant to normal C3H mouse tissue and were subsequently immunized with the Ehrlich ascites tumor. Nonpretreated rab bits were also immunized with tumor. In addition, both tolerant and nonpretreated rabbits were given similar injections of normal tissue antigens. It wasfoundthat, in smallamounts,both tolerantand nontolerantanti-Ehrlich ascites tumor se...
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Uptake and binding of daunorubicin were studied in a sensitive (EHR 2) and in a resistant (EHR 2/DNR+) subline of Ehrlich ascites tumor cells. At steady state, the celhmedium ratio of daunorubicin was about 10-fold higher in EHR 2 than in EHR 2/DNR + . The bindings of daunorubicin to cell homogenate of the two cell lines were equal when the concentration at equilibrium was below 0.7 fig/ml, whe...
متن کاملOn Perfused Ehrlich Ascites Tumor Cells
In an attempt to overcome resistance of hypoxic cells to radiotherapy, the combination of a hematoporphyrin derivative (Hpd) and 2-deoxy-D-glu'cose (2-DG), a promising radiomodifier, was evaluated by assessing the alterations in phosphorylated metabolites and bioenergetics induced in perfused Ehrlich :lscites tumor (EAT) cells, using Phosphorus31 Magnetic Resonance Spectroscopy (JiP-MRS). By re...
متن کاملThe utilization of unesterified palmitate by Ehrlich ascites tumor cells.
Ehrlich ascites tumor cells have been shown to take up long chain free fatty acids from albumin-FFA’ complexes very rapidly in vitro. The uptake during the 1st min of exposure of the cells is dependent on the FFA-albumin molar ratio in the medium (I? 2). Most of the FFA initially taken up is present in unesterified form, and at least 50% of it is reversibly bound (2). The initial FFA uptake is ...
متن کاملUptake of Free Fatty Acids by Ehrlich Ascites Tumor Cells.
Plasma free fatty acid is the form in which fat is transported from the adipose tissue for utilization (2). Almost all of the FFAI present in plasma is tightly bound in a noncovalent complex with albumin, and less than 0.01 y0 is present unbound (i.e. in free solution) under ordinary conditions (3). However, in spite of the high association constants for binding of FFA to albumin, FFA leave the...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1975
ISSN: 0002-1369
DOI: 10.1080/00021369.1975.10861652